Synthesis of High Fracture Toughness of Hydroxyapatite Bioceramics

Abstract:

The sinterability of magnesium oxide (MgO) doped hydroxyapatite (HA) ranging from 1 to 10 wt% when sintered at 1150°C was investigated in terms of phase stability, bulk density, Young’s modulus, Vickers hardness and fracture toughness. The addition of up to 1 wt% MgO as sintering additive was found to be beneficial in promoting the densification of HA. Further addition of MgO in the HA matrix would deteriorate its densification properties. Similar results were observed for its stiffness and Vickers hardness. Nevertheless, the fracture toughness of HA was greatly enhanced by the incorporation of 5 wt% MgO. An increased toughness of up to 35% was obtained for the MgO-doped HA when compared to the undoped HA. This improvement is associated to the smaller grain size of the doped sample as compared to the undoped HA.

• Periodical: Advanced Materials Research (Volumes 264-265)
• Pages: 1849-1855
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.264-265.1849
• Online since: June 2011
• Authors: Chou Yong Tan, Ramesh Singh, R. Tolouei, Iis Sopyan, Wan Dung Teng
• Keywords: Hydroxyapatite (HAP), Magnesium Oxide, Sinterability

References

[1] An, G.H., Wang, H.J., Kim, B.H., Jeong, Y.G. and Choa, Y.H., Fabrication and characterization of a hydroxyapatite nanopowder by ultrasonic spray pyrolysis with salt-assisted decomposition, Materials Science and Engineering: A, Vol. 449-451, 2007, pp.821-824.

DOI: 10.1016/j.msea.2006.02.436

[2] Ramesh, S., Tan, C.Y., Sopyan, I., Hamdi, M. and Teng, W.D., Consolidation of nanocrystalline hydroxyapatite powder, Sci. and Tech. Adv. Mater., Vol. 8, 2007, pp.124-130.

DOI: 10.1016/j.stam.2006.11.002

[3] Afshar, A., Ghorbani, M., Ehsani, N., Saeri, M.R. and Sorrell, C.C., Some important factors in the wet precipitation process of hydroxyapatite, Materials and Design, Vol. 24, 2003, pp.197-202.

DOI: 10.1016/s0261-3069(03)00003-7

[4] Jingbing, L., Ye, X., Wang, H., Zhu, M., Wang, B. and Yan, H., The influence of pH and temperature on the morphology of hydroxyapatite synthesized by hydrothermal method, Ceram. Inter., Vol. 29, 2003, pp.629-633.

DOI: 10.1016/s0272-8842(02)00210-9

[5] Bandyopadhyay, A., Withey, E.A., Moore, J. and Bose, S., Influence of ZnO doping in calcium phosphate ceramics, Materials Science and Engineering: C, Vol. 27, 2007, pp.14-17.

DOI: 10.1016/j.msec.2005.11.004

[6] Manjubala, I. and Kumar, S.S., Effect of TiO2–Ag2O additives on the formation of calcium phosphate based functionally graded bioceramics, Biomaterials, Vol. 21, 2000, p.1995-(2002).

DOI: 10.1016/s0142-9612(00)00092-2

[7] Zreiqat, H., Howlett, C.R., Zannettino, A., Evans, P., Schulze-Tanzil, G. and Knabe, C., Mechanisms of magnesium-stimulated adhesion of osteoblastic cells to commonly used orthopaedic implants, J. Biomed. Mater. Res., Vol. 62, 2002, pp.75-184.

DOI: 10.1002/jbm.10270

[8] Tan, C.Y., Aw, K.L., Yeo, W.H., Ramesh, S., Hamdi, M. and Sopyan, I., Influence of magnesium doping in hydroxyapatite ceramics, IFMBE Proceedings Biomed 2008 "4th Kuala Lumpur International Conference on Biomedical Engineering. (International Federation for Medical and Biological Engineering, Vol. 21, Springer-Verlag Berlin Heidelberg 2008: ISSN 1680-0737) p.326.

DOI: 10.1007/978-3-540-69139-6_83

[9] Ramesh, S., A method for manufacturing hydroxyapatite bioceramic, Malaysia Patent, (PI. 20043325) (2004).

[10] ASTM E1876-97, Standard test method for dynamic Young's modulus, Shear modulus and Poisson's ratio by impulse excitation of vibration, 1998, ASTM International.

DOI: 10.1520/e1876

[11] Niihara, K., Morena, R. and Hasselman, D.P.H., Evaluation of KIc of brittle solids by the indentation method with low crack-to-indent ratios, J. Mater. Sci. Letts., Vol. 1, 1982, pp.13-16.

DOI: 10.1007/bf00724706

[12] Staiger, M.P., Pietak, A.M., Huadmai, J. and Dias, G., Magnesium and its alloys as orthopedic biomaterials: A review, Biomaterials, Vol. 27, 2006, pp.1728-1734.

DOI: 10.1016/j.biomaterials.2005.10.003

[13] Hench, L.L., Bioceramics: from concept to clinical, J. Am. Ceram. Soc., Vol. 74, 1991, pp.1487-1510.

[14] Duan, Y., Wang, C., Cheng, J. and Zhang, X., Bone-like apatite formation in intramuscularly implanted calcium phosphate ceramics in different kinds of animal, J. Mater. Sci. Lett., Vol. 21, 2002, pp.775-778.

[15] Flautre, B., Descamps, M., Delecourt, C., Blary, M.C. and Hardouin, P., Porous HA ceramic for bone replacement: Role of the pores and interconnections – Experimental study in the rabbits, J. Mater. Sci.: Mater. Med., Vol. 12, 2001, pp.679-682.

DOI: 10.1023/a:1011256107282

[16] Rivera-Munoz, E., Diaz, J.R., Rodriguez, J.R., Brostow, W. and Castano, V.M., Hydroxyapatite spheres with controlled porosity for eye ball prosthesis: Processing and characterization, J. Mater. Sci.: Mater. Med., Vol. 12, 2001, pp.305-311.